One of the frequent causes of non-traumatic lower-limb amputation is Diabetes and is usually preceded by foot ulcer and infection. The reason of this ulceration is commonly a loss of protective sensation due to peripheral neuropathy, for which there is no prevention strategy. Current research promotes early detection of neuropathy so that secondary prevention measures, such as intensive foot-care education and treatment, can be used for individuals.
In an effort to standardize and simplify the detection of insensate foot, the 5.07/10-gm Monofilament is recommended by the International Diabetes Federation and the World Health Organization as a device that can be used by health professionals at every level of care.
A standardised filament is pressed against part of the foot. When the filament bends, its tip is exerting a pressure of 10 grams (therefore this monofilament is often referred to as the 10 gram monofilament). If the patient cannot feel the monofilament at certain specified sites on the foot, he/she has lost enough sensation to be at risk of developing a neuropathic ulcer.